Introduction to
Protein Structure Bioinformatics 2004

  • Registration is closed

Overview of the course program

  • Principles of Protein Structure
    • Properties of amino acids and peptide bonds
    • Physics and Chemistry of Molecular Interactions
    • Secondary Structures
    • Tertiary and Quaternary Structure
    • Protein Fold Classification (SCOP, CATH, etc.)
    • Protein Folding

  • Experimental Structure Solution
    • by X-ray crystallography
    • by NMR Spectroscopy

  • Visualization and Analysis
    • Atomic and schematic Representations of proteins
    • Structural Superposition
    • Molecular Surfaces
    • Electrostatics
    • High quality Imaging (for publications)

  • Protein Structure Bioinformatics
    • Secondary Structure Prediction
    • Fold Recognition
    • Threading
    • Homology Modeling (rigid fragment assembly, satisfaction of spatial restraints)
    • Molecular Dynamics
    • Molecular Modeling