Three-dimensional protein structures are key to a detailed understanding
of the molecular basis of protein function. Combining sequence information
with 3D structure gives insights for the development of effective
rational strategies for experiments such as site directed mutagenesis,
studies of disease related mutations, or the structure based design
of specific inhibitors.
Biological and biomedical research scientists and
graduate students without prior training in the field of protein
The goal of this course is to expose the participants to 3-dimensional
structures of macromolecules, especially proteins. It describes the
experimental methods used to solve these structures, and databases
used to archive, annotate and classify protein structures. Analysis
and visualitation softwares will be used to display, analyze, compare
and interpret protein structures. The second part of the course is
dedicated to protein structure prediction and molecular simulations.
The course was held from February 19 to February 23, 2007 and formally announced through the embnet-news
mailing list. The registration form is available here.
The schedule is available here.
Location, housing and transportation